Mesothelioma Treatment - New Treatment Found


Mesothelioma is the greatest conspiracy by all government agencies along with manufacturers in the 60s and 70s to kill you and your family slowly through Asbestos Exposure. And they all knew what Asbestos could do to you in your job and in your home, but they all said "No Worry". And so today there is some good news, because there is a possible new treatment found for Mesothelioma... SEE


Studies report new findings on treatment options for mesothelioma 
European Society for Medical Oncology News, 

High–dose radiotherapy adds no survival benefit after chemotherapy and radical surgery; PD–L1 protein a possible immunotherapy target. The multicentre trial included 153 patients with surgically–treatable malignant pleural mesothelioma, who were first treated with three chemotherapy cycles of cisplatin and pemetrexed, followed by surgical removal of affected lung tissue, with the goal of complete removal of the cancerous areas of lung. In a second part of the study, researchers randomly assigned 54 patients to receive either radiotherapy or no further treatment, with the primary endpoint being the duration of relapse–free survival. While there had been preliminary evidence suggesting that the addition of radiotherapy might improve outcomes, the study failed to find any differences in relapse–free survival between patients treated with the additional radiotherapy, and those who were not. Stahel says researchers were hoping for a more positive signal from the study. “We aimed for a six month delay in local recurrence, which would be meaningful because it’s an aggressive treatment for patients.” In summary, Stahel says, “It demonstrates that, like in other solid tumours, when two modalities are not sufficient it’s very rare that the third modality added would make a benefit.” In a second study presented at the ESMO 2014 Congress, researchers report that about 20% of patients with malignant pleural mesothelioma have cancer cells that express a protein called programmed cell–death ligand 1 (PD–L1) that is associated with poorer outcomes. The results suggest this population of patients could be treated with targeted therapies to PD–L1, researchers say.
credit: http://www.mdlinx.com/oncology/news-article.cfm/5592908



Biomolecular and clinical practice in malignant pleural mesothelioma and lung cancer: What thoracic surgeons should know 
European Journal of Cardio-Thoracic Surgery,   Clinical Article

Opitz I, et al. – The European Society of Thoracic Surgeons (ESTS) Biology Club aims at providing a comprehensive insight into the basic biology of the diseases physicians are treating. During the 2013 ESTS Annual Meeting, different experts of the field presented the current knowledge about diagnostic and prognostic biomarkers in malignant pleural mesothelioma including new perspectives as well as the role and potential application of microRNA and genomic sequencing for lung cancer, which are summarized in the present article.




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